Bryan Mbeumo (captain), Brentford, £8.1m – Manchester United (h)
You don’t need much of a reason to pick Mbeumo, FPL’s second-highest points scorer.
But the situation this week is a dream scenario.
Manchester United are almost certainly going to put out a weakened team, with their focus on the Europa League, and it is not like they have been great.
Mbeumo is in form, he takes penalties, is Brentford’s talisman and might be up against 18-year-old left-back Harry Amass.
Jarrod Bowen, West Ham, £7.6m – Spurs (h)
Another in-form player (four returns in four games) in a similar scenario to Mbeumo.
Tottenham will be focused on Europe – and they can’t defend anyway.
Bowen has been involved in 56% of West Ham’s goals this season.
Kevin de Bruyne, Manchester City, £9.4m – Wolves (h)
Neither of the three expensive midfielders – Mohamed Salah, Cole Palmer and Bukayo Saka – have ideal match-ups this week.
Chelsea v Liverpool is very difficult to call given the Reds have wrapped up the title, and Arsenal’s Saka could easily start on the bench.
So why not look at De Bruyne, who will surely play after being rested in the FA Cup in a game that could be high-scoring.
The great Belgian has nine assists this season in only 16 starts – with 0.56 assists per 90 minutes played.
As long as he starts you can feel confident of a return and, with only two home games of his City career left, surely Pep Guardiola selects him on Friday night.
Marco Asensio, Aston Villa, £6.2m – Fulham (h)
Morgan Rogers is the popular Villa pick but Asensio is the high-risk, high-reward choice.
Since he arrived he has topped every stat among Villa midfielders.
The Spaniard has taken 3.56 shots per 90 minutes on the pitch (Rogers is 1.56) and his xG per 90 is 0.78. Rogers is next best on 0.24.
Asensio has 6.96 FPL points per 90 – and don’t forget he missed two penalties.
The issue is game time, but Marcus Rashford’s injury should make Asensio’s path to the first XI smoother – and there are big rewards waiting if you take a punt.
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